Dr. Marianne Koritzinsky Publications

  1. Koontz, BF, Koritzinsky, M, Zoberi, JE, Brown, SL, Ding, X, Wong, J, Joiner, MC, Dominello, MM, Burmeister, J (2024). Three discipline collaborative radiation therapy (3DCRT) special debate: Systemic radiotherapy using targeted isotopes is the best hope for advancing curative radiation therapy. J Appl Clin Med Phys25,e14533.
  2. Lee, SCS, Pyo, AHA, Mohammadi, H, Zhang, J, Dvorkin-Gheva, A, Malbeteau, L, Chung, S, Khan, S, Ciudad, MT, Rondeau, V et al. (2024). Cysteamine dioxygenase (ADO) governs cancer cell mitochondrial redox homeostasis through proline metabolism. Sci Adv10,eadq0355.
  3. Ci, X, Chen, S, Zhu, R, Zarif, M, Jain, R, Guo, W, Ramotar, M, Gong, L, Xu, W, Singh, O et al. (2024). Oral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer. BMC Cancer24,744.
  4. Ciudad, MT, Quevedo, R, Lamorte, S, Jin, R, Nzirorera, N, Koritzinsky, M, McGaha, TL (2024). Dabrafenib Alters MDSC Differentiation and Function by Activation of GCN2. Cancer Res Commun4,765-784.
  5. Lee, SCS, Pyo, AHA, Koritzinsky, M (2023). Longitudinal dynamics of the tumor hypoxia response: From enzyme activity to biological phenotype. Sci Adv9,eadj6409.
  6. Ciudad, MT, Quevedo, R, Lamorte, S, Jin, R, Nzirorera, N, Koritzinsky, M, McGaha, TL (2023). Dabrafenib alters MDSC differentiation and function by activation of GCN2. bioRxiv,.
  7. Jiang, Z, Ju, Y, Ali, A, Chung, PED, Skowron, P, Wang, DY, Shrestha, M, Li, H, Liu, JC, Vorobieva, I et al. (2023). Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer. Nat Commun14,4313.
  8. Kondratyev, M, Pesic, A, Ketela, T, Stickle, N, Beswick, C, Shalev, Z, Marastoni, S, Samadian, S, Dvorkin-Gheva, A, Sayad, A et al. (2023). Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer. Commun Biol6,538.
  9. Marastoni, S, Madariaga, A, Pesic, A, Nair, SN, Li, ZJ, Shalev, Z, Ketela, T, Colombo, I, Mandilaras, V, Cabanero, M et al. (2022). Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer. Cancer Res Commun2,293-306.
  10. Han, K, Fyles, A, Shek, T, Croke, J, Dhani, N, D'Souza, D, Lee, TY, Chaudary, N, Bruce, J, Pintilie, M et al. (2022). A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer. Clin Cancer Res28,5263-5271.
  11. Dimitriou, ID, Meiri, D, Jitkova, Y, Elford, AR, Koritzinsky, M, Schimmer, AD, Ohashi, PS, Sonenberg, N, Rottapel, R (2022). Translational Control by 4E-BP1/2 Suppressor Proteins Regulates Mitochondrial Biosynthesis and Function during CD8 T Cell Proliferation. J Immunol208,2702-2712.
  12. Lam, KHB, Leon, AJ, Hui, W, Lee, SC, Batruch, I, Faust, K, Klekner, A, Hutóczki, G, Koritzinsky, M, Richer, M et al. (2022). Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity. Nat Commun13,116.
  13. Wong, CS, Chu, W, Ashamalla, S, Fenech, D, Berry, S, Kiss, A, Koritzinsky, M (2021). Metformin with neoadjuvant chemoradiation to improve pathologic response in rectal cancer: A pilot phase I/II trial. Clin Transl Radiat Oncol30,60-64.
  14. Mahendralingam, MJ, Kim, H, McCloskey, CW, Aliar, K, Casey, AE, Tharmapalan, P, Pellacani, D, Ignatchenko, V, Garcia-Valero, M, Palomero, L et al. (2021). Mammary epithelial cells have lineage-rooted metabolic identities. Nat Metab3,665-681.
  15. Jain, P, Dvorkin-Gheva, A, Mollen, E, Malbeteau, L, Xie, M, Jessa, F, Dhavarasa, P, Chung, S, Brown, KR, Jang, GH et al. (2021). NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4. Sci Adv7,.
  16. Levitin, F, Lee, SCS, Hulme, S, Rumantir, RA, Wong, AS, Meester, MR, Koritzinsky, M (2021). Oxygen-independent disulfide bond formation in VEGF-A and CA9. J Biol Chem296,100505.
  17. Cheung, S, Jain, P, So, J, Shahidi, S, Chung, S, Koritzinsky, M (2021). p38 MAPK Inhibition Mitigates Hypoxia-Induced AR Signaling in Castration-Resistant Prostate Cancer. Cancers (Basel)13,.
  18. Liang, Y, Jeganathan, S, Marastoni, S, Sharp, A, Figueiredo, I, Marcellus, R, Mawson, A, Shalev, Z, Pesic, A, Sweet, J et al. (2021). Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies. Clin Cancer Res27,2340-2351.
  19. Patel, PS, Vyravanathan, S, Milne, E, Bezjak, A, Wouters, BG, Bennewith, K, Seuntjens, J, Liu, ZA, Harding, SM, Liu, FF et al. (2021). Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21): 15-Year Evaluation of an Innovative Research Training Program. Int J Radiat Oncol Biol Phys110,656-666.
  20. Li, YQ, Koritzinsky, M, Wong, CS (2020). Metabolic Regulation of Hippocampal Neuroprogenitor Apoptosis After Irradiation. J Neuropathol Exp Neurol79,325-335.
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