Lab Members2

Principal Investigators

Brad Wouters

PhD

Professor

 

Marianne Koritzinsky

PhD

Associate Professor

Staff

Stephen Chung

Lab Manager

Julie Owens

Administrative Assistant

Anthony Joshua

MBBS, PhD

Affiliate Scientist

Stefano Marastoni

PhD

Scientific Associate

Stefano is a member of the Wouters and Joshua labs. He completed his PhD in Clinical Sciences in Italy and is currently a Scientific Associate.

Stefano’s research is focused on drug repurposing, drug development and targeting of lysosomal biology in cancer.

Ravi Vellanki

PhD

Scientific Associate

Ravi is a member of the Wouters lab. He completed his PhD in biotechnology and is currently a Scientific Associate.

Ravi’s research interests include R&D of cancer cell signaling, chemical probes, small molecule inhibitors and formulations.

Rob Cairns

PhD

Scientific Associate

Rob is a member of the Wouters lab. He completed his PhD in Medical Biophysics at the University of Toronto and is currently a Scientific Associate.

Rob has long standing interest in the tumor microenvironment and tumor metabolism, with a focus on the role of oxygen. His work has focused on the effects of the tumor microenvironment on metabolism and on identifying opportunities to manipulate the tumor microenvironment to achieve improved clinical outcomes.

Lucie Malbeteau

PhD

Postdoctoral Fellow

Lucie is a member of the Koritzinsky lab. She completed her PhD at the Université of Lyon, in France and is currently a Postdoctoral Fellow.

Lucie’s project investigates whether disrupting redox homeostasis drives the activation of innate immunity signaling in pancreatic cancer and can be fully harnessed in combination with radio- and immune-therapy. She has a particular interest in one anti-oxidant protein, PRDX4.

 

Ronald Wu

PhD

Postdoctoral Fellow

Ron is a member of the Wouters lab. He completed his PhD in the department of Medical Biophysics at the University of Toronto and is currently a Postdoctoral Fellow.

Jasmine Randhawa

MSc

Research Technician II

Jasmine is a member of the Koritzinsky lab. She completed her Masters at McGill University and is currently a Research Technician.

During her graduate degree, Jasmine’s research was focused on female reproductive physiology. Specifically, she conducted her research on mice models to explore the role of Cnr1 receptor in ovarian granulosa cells. As a technician, she now plays a key role in supporting all in vivo work ongoing in the lab.

 

Andrea Pyo

MSc

Research Technician I

Aleksandra Pesic

Research Technician II

Graduate Students

Jasmine Randhawa

MSc

Research Technician II

Jasmine is a member of the Koritzinsky lab. She completed her Masters at McGill University and is currently a Research Technician.

During her graduate degree, Jasmine’s research was focused on female reproductive physiology. Specifically, she conducted her research on mice models to explore the role of Cnr1 receptor in ovarian granulosa cells. As a technician, she now plays a key role in supporting all in vivo work ongoing in the lab.

 

Andrea Pyo

MSc

Research Technician I

Aleksandra Pesic

Research Technician II

Graduate Students

Jasmine Randhawa

MSc

Research Technician II

Jasmine is a member of the Koritzinsky lab. She completed her Masters at McGill University and is currently a Research Technician.

During her graduate degree, Jasmine’s research was focused on female reproductive physiology. Specifically, she conducted her research on mice models to explore the role of Cnr1 receptor in ovarian granulosa cells. As a technician, she now plays a key role in supporting all in vivo work ongoing in the lab.

 

Andrea Pyo

MSc

Research Technician I

Aleksandra Pesic

Research Technician II

Graduate Students

Ji Zhang

PhD Candidate

Graduate Student

Ji is supervised by Dr. Wouters. He completed his undergraduate degree in Human Biology from the University of Toronto. He is currently a PhD candidate in the Department of Medical Biophysics at the University of Toronto.

The genetic drivers determining an individual tumour’s hypoxia level is currently unknown. Ji’s research is focused on using a matching panel of primary PDAC, patient-derived-xenografts, and organoids, to create a predictive model of tumour hypoxia consisting of the genes/pathways driving cellular oxygen consumption rate, hypoxia tolerance, and perfusion

 

Mark Zaidi

PhD Candidate

Graduate Student

Mark is supervised by Dr. Wouters. He completed his undergraduate degree in Biology with a specialization in Zone Learning from Ryerson University. He is currently a PhD candidate in the Department of Medical Biophysics at the University of Toronto.

Mark is focused on developing personalized image analysis workflows for analyzing high dimensionality and multi modal imaging datasets, with a specific focus on imaging mass cytometry (IMC), CODEX, and spatial transcriptomics.

 

Saeid Shahidi

PhD Candidate

Graduate Student

Saeid is supervised by Dr. Koritzinsky. He completed his Masters degree from Simon Frasier University. He is currently a PhD candidate in the Institute of Medical Sciences at the University of Toronto.

Saeid is focused on studying the potential role of the Mitochondria-Associated Membrane (MAM) in the secretome profile of glioblastoma cells

 

Emily Poulton

PhD Candidate

Graduate Student

Emily is supervised by Dr. Koritzinsky. She completed her undergraduate degree in Human Biology at the University of Toronto. Shee is currently a PhD candidate in the Department of Medical Biophysics at the University of Toronto.

Emily is focused on understanding the role of redox homeostasis and antioxidants within the context of pancreatic cancer.

 

Aesha Patel

MSc Candidate

Graduate Student

Phoebe Lombard

MSc Candidate

Graduate Student

Phoebe is supervised by Dr. Wouters. She completed her undergraduate degree in BLANK from BLANK. She is currently a Master’s candidate in the Department of Medical Biophysics at the University of Toronto.

Phoebe is studying the spatial organization of transcriptional states in glioblastoma.

Vishal Pandya

MSc Candidate

Graduate Student

Vishal is supervised by Dr. Koritzinsky. He completed his undergraduate degree in Neuroscience from McMaster University. He is currently a Master’s candidate in the Institute of Medical Sciences at the University of Toronto.

Vishal’s project involves understanding if/how metabolic stress can initiate anti-tumour immune responses in pancreatic cancer.

 

Favian Retnavarathan

MSc Candidate

Graduate Student

Favian is supervised by Dr. Koritzinsky. He completed his undergraduate degree at the University of Toronto in Molecular Genetics and Cell and Molecular Biology. He is currently a Master’s candidate in the Institute of Medical Sciences at the University of Toronto.

Favian’s project looks at the role that nutrients and metabolites play in disulfide bond formation under hypoxic conditions. He is investigating whether nutrients or metabolites play a role in being the terminal oxidant to drive protein folding in the absence of molecular oxygen.

Undergraduate Students & Volunteers

Patrick Policicchio

Undergraduate Thesis Student

Patrick is supervised by Dr. Wouters. He is completing his undergraduate degree in Life Sciences from the University of Toronto.

Patrick is exploring the relationship between oxygen consumption rate in PDAC and radiosensitization by OXPHOS Inhibition.

Isabel Hodara

Co-op Student

Isabel is supervised by Dr. Koritzinsky. She is currently a high school co-op student.

Isabel is focused on learning and mastering basic wet lab techniques such as Western Blotting, protein extraction, tissue culture, etc.

 

Favian Retnavarathan

MSc Candidate

Graduate Student

Favian is supervised by Dr. Koritzinsky. He completed his undergraduate degree at the University of Toronto in Molecular Genetics and Cell and Molecular Biology. He is currently a Master’s candidate in the Institute of Medical Sciences at the University of Toronto.

Favian’s project looks at the role that nutrients and metabolites play in disulfide bond formation under hypoxic conditions. He is investigating whether nutrients or metabolites play a role in being the terminal oxidant to drive protein folding in the absence of molecular oxygen.